The University of Wisconsin–Madison’s academic and scientific environment extends its infrastructure and expertise to business and industry. Join other Wisconsin and U.S clients and find a solution to advance your business needs with contracted development at UW.
Explore our areas of expertise and contact OBE by email or phone: 608-263-2840.
The UW Carbone Cancer Center Drug Discovery Core (DDC) »
- Facilitates cancer-related preclinical drug discovery
- Integrates high throughput screening, medicinal chemistry, pharmocology.
Small Molecule Screening Facility | Cancer Pharmacology Lab | Medicinal Chemistry
Flow Cytometry »
- Single cell analysis
- Single cell sorting: single cell deposition and bulk sorting of live cells
- Comprehensive assay services: sample prep, data acquisition and analysis for immunophenotyping, cell cycle, DNA content, apoptosis, phagocytosis, calcium flux, cytokine and phosphoprotein detection, mitochondrial membrane potential, oxidative burst
Histology/Pathology »
- Microtomy and cryo sectioning; H&E and special stains
- IHC protocol development and optimization
- Expert “in house” pathology consultation
- Histologic staining methods to histopathologic assays
- DNA/RNA isolation, quantitative real time RT-PCR analysis
- Standardized IHC/IF/ISH through automation
- Multispectral imaging system NuanceTM (manual) and VectraTM (automated) imaging
Formulation and Characterization »
- Drug, biologic and excipient physical/chemical characterization (pre-formulation)
- Formulation
- Analytical method development and validation
- Stability testing
- Structural elucidation
Biomanufacturing »
- Plasmid DNA Production
- Recombinant Protein Production
- Cell Therapeutics Production
- Viral Vector/Vaccine Production
- Aseptic Fill/Finish
Small Animal Imaging »
- Noninvasive, high-resolution in-vivo and ex-vivo
- 2-D and 3-D image viewing
- microCT and micro MRI (anatomical and functional)
- microPET and optical imaging (functional)
- Intraoperative Real Time Near-Infrared optical imaging (functional)
- Imaging of targeted, non-targeted, vascular, and activatable contrast agents